Over the past 30 years or so, U.S. venture capitalists and investors have enjoyed attractive returns of 17% to 18%, says Josh Lerner, a Harvard Business School professor and co-author with Harvard colleague Paul Gompers of The Money of Invention: How Venture Capital Creates New Wealth. Returns peaked at 190% during the dot-com boom in 1999 and hit 20% last year.

The investments are high-risk, though, and the most lucrative returns are taken by mostly larger venture firms, Lerner says. And returns have slowed in recent years because of the weak financial markets.

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